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*Correspondence: Franziska Weichmann, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

The rationale for adding it to tirzepatide is that calorie restriction and GI side effects from GLP-1 medications can reduce B12 absorption, potentially leading to deficiency over time

More recently, Mn was found to increase LRRK2 expression, a protein associated with Parkinsons Disease, in vitro and in vivo , while LRRK2 deletion in microglia reduced cytokine release in vitro (Kim et al., 2019)

The key difference is that Synjardy adds empagliflozin